• UNIT 1
• UNIT 2
• UNIT 3
• UNIT 4
• DNA & GENOMICS REVIEW

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UNIT 1: How to Fight Infection

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1.1 - The Mystery Infection

1.1.1 Medical Interventions

• ​Medical Interventio​ns: Color Changing Band-aid
• Science: 2015 Breakthrough of the year
• Types of Medical Interventions

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1.1.2 Investigating an Outbreak​

• RadioLab: Patient Zero Podcast
• Video Animation of a Cell​
• Controlling an Outbreak
• Game: ​CDC Solve the Outbreak!

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1.1.3 Identifying Pathogens​

• What is a BLAST?
• BLAST search
• What is PCR?
• PCR technique explained
• ​PCR In more detail, step by step
• PCR Video Explanation
• PCR Video of Steps
• Learn.Genetics: PCR Simulation
• DNA Learn Center: DNA Sequencing
• Essential Biochemistry Animation: DNA Sequencing
• Video: Sanger Method of DNA Sequencing
• Interactive: Sanger Method

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1.1.4 Concentrations​

• How to Do Serial Dilutions
• Serial Dilution Animation & Video

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1.1.5 ELISA

• Cells of the Immune System
• What is the Antigens-Antibody Complex?
• Antigens & Antibodies: Detailed Overview
• Antibody Interaction: Video
• Immune System Overview
• B Cell Activation Video
• B and T Cell Overview
• B and T Cell: In Depth (Khan Academy)
• The Immune Response: Video
• Immune Response Animation Video
• Video: What is ELISA?
• BioRad: ELISA Antibody and Antigen Detection
• McGraw-Hill: ELISA video and quiz
• Immunology: ELISA Intro and Explanation
• ELISA Overview: Types of ELISA Explained
• BioMedHead: ELISA Resources
• hCG Elisa explanation
• TedED: Home Pregnancy Test explanation
• BBC: Defending against infection
• Bio Crash Course: Your Immune System- Natural Born Killer
• Bacterial Infection: Immune System Explained

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1.2 - Antibiotic Treatment

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1.2.1 Antibiotic Therapy

• CellsAlive! Bacterial Structure Interactive
• Bacterial Cell Structure & Function
• Northern Illinois University: Bacterial structure ppt
• Bacterial Plasmids Detailed Explanation
• Biotech Learning Hub: The Role of Plasmids 
• Gram Positive vs. Gram Negative: Video Explanation
• Endotoxin vs. Exotoxin
• History of Antibiotics
• Antibiotic Attack!
• Video: History of Penicillin
• Microbiological Techniques
• How to Put Bacteria on a Petri Dish
• Aseptic Technique: Video
• How antibiotics kill bacteria & not human cells
• Antibiotics Mode of Action
• TedEd: What causes Antibiotic Resistance?

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1.2.3 Super Bugs!

• Cipro on the Farm: Animation of Antimicrobial Resistance​
• WHO: Antimicrobial Resistance
• The Golden Age of Antibacterials: Timeline
• Nature Article: Antibiotic Resistance, The Last Resort
• Consumer Reports: The Rise of the SuperBugs
• CBS: 15 Superbugs & Diseases
• McGraw-Hill: Bacteria Conjugation Animation; ​Animation #2
• Plasmid Replication: Rolling Circle Mechanism Video
• Pearson: Bacterial Transformation
• McGraw-Hill: Bacterial Transformation Animation
• McGraw-Hill Generalized: Bacterial Transduction
• American Society of Microbiology Animation: Transduction Animation
• DNA Learning Center: DNA Transformation
• Sulfonamide Antibiotic: PABA Explanation
• Targets of Antibiotics

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1.2.4 Antibiotics & Antibiotic Failure

• Learn.Genetics: What is an Antibiotic?
• How Antibiotics Work: Video
• TED Video: What Causes Antibiotic Resistance?
• How Antibiotics Work: Explanation and History
• Antibiotic Attack Animation​
• Article: An Alternative to Antibiotics
• CDC 2013: Antibiotic Resistant Threats
• FDA: Combating Antibiotic Resistance
• How antibiotics target bacterial cells and not human cells
• How Penicillin Kills Bacteria (watch video)
• Class of Antibiotic Most Effective Against Gram Neg Bacteria

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1.3 - The Aftermath - Hearing Loss

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1.3.1 Good Vibrations

• Ear Diagram: Interactive
• How the Ear Hears
• Hearing Structures & Functions
• Label the Ear practice
• Sound Properties

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1.3.2​ Can You Hear Me Now?

• Hearing Test: Can You Hear This?
• Hearing Loss
• Conductive Hearing Loss
• Bone Conduction
• How Bone Conducting Headphones Work
• Try it: Hearing Test
• The Rinne Test
• Understanding an Audiogram
• How to read an Audiogram Explanation
• Hearing Loss (types, explanation, causes)
• How does hearing work?

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1.3.3 Cochlear Implant Debate

• How the Ear Works & Hearing Loss
• Cochlear Implants
• Hearing Aids
• An example of hearing loss video
• 3 types of hearing loss video
• Do I really sound like that?
• How old are your ears?
• Scientific American: Hearing Aids Meet the Future with Bluetooth

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1.4 - Vaccination

1.4.1 Vaccinations

• History of Vaccines: How Vaccines Work
  • Different Types of Vaccines Explanation
  • Types of Vaccines Visual
  • How Vaccines are Made
  • Herd Immunity Animation
• CDC: Vaccines
• History of Vaccines: Edward Jenner 100 greatest discoveries

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1.4.2 Vaccine Development

• Vaccines.org: Types of Vaccines
• DNAi: Recombinant DNA Review
• Antiviral Development
• Vaccines Given by Age
• Making vaccines video
• WHO: Immune Response to Vaccinations
• Vaccines by Sound Waves 

• Vaccination Debate: Part I; Part II
• Science Video: The riskiest vaccine? The one not given
• Vaccines do not cause Autism
• Data Falsification of Vaccines
• DNA Ligase
• Review of Restriction Enzymes
• How Recombinant DNA Works

Vaccine Debate:

• Vaccine Schedule by State w/Ingredients

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1.4.3 Epidemiologist

• Roles & Responsibilities

UNIT 2: Screen What's in Your Genes

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2.1 - Genetic Testing & Screening

2.1.1 Chronicles of a Genetic Counselor

• ​Genetic Counseling
• ​NOVA: Testing Tay Sachs Video

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2.1.3 Testing YOUR Genes

• PCR Animation
• Learn. Genetics Making SNP's Make Sense
• DNA Learning Center: PCR Animation
• PTC Taste & Genes

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2.1.5 Maternal Testing

• Amniocentesis
• CVS
• Prenatal Screening Risks & Benefits
• Karyotype and Genetic Disorders
• Karyotype Examples
• Using a Karyotype to Diagnose Disorders

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2.2 - Our Genetic Future

2.2.1 Gene Therapy

• What is Gene Therapy?
• Gene Therapy: Space Doctor
• Learn. Genetics Gene Delivery Vectors
• BBC: Designer Baby Debate
• Genetic Ethics​

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2.2.2​ Reproductive Technology

• Reproductive Cloning
• National Geographic Video: Clone​
• Therapeutic Cloning​

UNIT 3: How to Conquer Cancer

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3.1 - Detecting Cancer

3.1.1 Who is affected by cancer?

• ​Cancerous Cells
• Cells Behaving Badly
• Causes of Cancer
• Microscopic Appearance of Cancer Cells

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3.1.2 Diagnostic Imaging

• ​Cancer Treatment Diagnostic Imaging Videos:
  • ​X-Ray
  • CT Scan
  • MRI
  • Bone Scan
  • Biopsy
  • PET Scan
• Differences between X-ray, CT and MRI
• Cancer Diagnostic Tests

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3.1.3 When Cells Lose Control

• ​Metatasis (view slideshow @ bottom of the screen)
• Apoptosis
  • Cells Alive video "Dance of Death"
  • Apoptosis Animation Video
• HeLa cells
• Cellular Division
• How cancer cells divide
• Transformation from normal to cancer cells
• Proto-oncogenes vs. Oncogenes
• Tumor supressor cells/gen​es

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3.1.4 Microarray

• ​p53 Role in the cell
• Intro to DNA Microarrays with Animation
• Making a Microarray: Explanation video
• DNA Microarray Simulation
• HHMI: How to Analyze Microarray Data
• Learn. Genetics: Microarray Simulation

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3.1.5 Gene Expression

• Gene Expression
  • Short explanation with video​

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Eukaryotic Gene Expression

• DNA Methylation vs. Histone Acetylation
• Khan Academy Eukaryotic Gene Regulation
• Agouti Mice Epigenetics
• What is Epigenetics? Video
• Transcription Animation
• Enhancer Explanation and Animation/Quiz
• Post-transcriptional Control
• Post-translational Modifications - Khan Academy
• Gene Expression Animation

Using Bioinformatics: Gene Expression

• cDNA Libraries
• NCBI
• Ensembl
• UCSC Genome Browser
• Encyclopedia of DNA Elements (ENCODE  Project)
• VISTA

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3.2 - Reducing Cancer Risk

3.2.1​ Risk Factors

• Risk factors for Cancer
• The Genetics of Cancer
• National Cancer Institute: Causes & Prevention Research
• Cancer Prevention
• Marker Analysis
• Short Tandem Repeats Video

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3.2.2 Yeast Cells (Skin Cancer)

• Suspicious moles
• Skin Cancer:
  • ABCDE
  • Melanoma

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3.2.3 Breast Cancer

• ​Treatment
• Risk Factors
• Video: BCRA Gene Dr. Seuss
• Double Mastectomy: Angelina Jolie

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3.2.4 Virology

• American Society of Virology

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3.2.5 Scanning

• Cancer.org: Cancer Screening
• CDC: Cancer Screening Tests
• Early Detection & Screening for Breast Cancer
• Cancer Prevention: Mammograms
• Cancer Screening Guideline​

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3.3 - Treating Cancer

3.3.1 Cancer Diary

• BBC: Harnessing the Immune System to Fight Cancer
• American Cancer Society: Chemotherapy
• Chemotherapy Cooling Cap to Prevent Hair Loss
• NIH: Radiation Therapy
• A Guide to Radiation Therapy
• Cancer Treatment Video
• Radiation Therapy to Treat Cancer Video
• Giving Viruses a License to Kill Cancer Video
• Chemotherapy Medical Animation
• Cancer Survivor Explains Rotationplasty​

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3.3.2 Biofeedback

• Biofeedback Effects of Stress: Methods on how to Relax
• Online Relaxation Exercises

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3.3.3 Prosthetic Arm

• Prosthetic Arm:
  • bebionic
  • Hopkins Applied Physics Lab 
  • Quartz Prosthetic Robot Arm
• Deka Arm
  • Video
• The Bionic Man video

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3.3.4 Physical & Occupational Therapy

• Physical Therapy
• Occupational Therapy

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3.4 - Building a Better Cancer Treatment

3.4.1 Personalized Medicine

• Personalized medicine
• Learn. Genetics: Pharmacogenetics
• Learn.Genetics: Prescision Medicine

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3.4.2 Nanofuture

• TEDTalks: Future of Medicine
• Respirocytes
  • Definition

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3.4.3 Clinical Trials

• Medline: Clinical trials
• NIH Clinical Trials

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3.4.4 Tiny Treatment

• Nanotechnology tricking cancer cells
• Video: Nanotechnology with Stephen Fry
• Nanomedicine to Fight Cancer: Video
• Science Jan 2017: Nanoparticles awaken immune cells to fight cancer

UNIT 4: Prevail When Organs Fail

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4.1 - Manufacturing Human Proteins

• Recombinant DNA with Insulin
• Article: Bacteria are Genetically Modified by Lightning
• DNA Transformation
• pGLO Transformation Guide
• BioRad pGLO Tranfsormation and Protein Purification ppt
• Chromatography
• Animation: Protein Chromatography
• Protein Purification by Chromatography Video Explanation
• Amino Acid Structures
• Protein Folding Explanation
• Help Standford: Protein Folding ID 
• Protein Folding Interactive
• Protein electrophoresis Animation
• Pearson Protein Structure Animation
• Video: SDS Gel Electrophoresis
• SDS Page Step by Step Animation
  • Biology Animation #2

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4.2 - Organ Failure

• Normal Blood Levels
• Urinalysis
• ERSD

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4.3 - Transplant

• Blood Groups & Typing
• Blood Typing Explanation & Practice: A, B, O Analysis
• HLA Testing
• PRA 
• Laproscopy
• Minimally Invasive Surgery
• Laproscopic Surgery: How its Performed
• ​Basic Suturing Technique Video
• Simple Interrupted Suture Video

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4.4 - Building a Better Body

• Bionic Human
• Bionic Spine Video
• The Six Million Dollar Man
• 08/01/15: Blind woman gets a Bionic eye
• How the bionic eye works
• Interactive: Organ transplants
• Tissue engineering
• Tissue regeneration
• Xenotransplantation
• Would you accept a pig organ to save your life?
• Nature article: The boom in mini-organs 
• The Economist: Organ printing

DNA REVIEW

DNA STRUCTURE:

• BioMedHead: DNA Review
• DNA Structure YouTube Video
• DNA Structure Explained
• Khan Academy: DNA Molecular Structure Video
• Science: 3D Chromatin Structure & Visualization

DNA REPLICATION:

• Khan Academy: DNA Replication Review
• DNA Polymerase & Replication: video
• McGraw-Hill DNA Replication Fork animation
• McGraw-Hill DNA Replication w/Quiz
• DNA Replication Video
• DNA Replication Video #2
• Amoeba Sisters: DNA Rep

PCR (Polymerase Chain Reaction):

• What is PCR?
• PCR Video Animation
• PCR 3-D Animation
• Cold Spring Harbor Interactive
• HHMI PCR Interactive
• Khan Academy PCR Video
• Khan Academy PCR Explanation

PROTEIN SYNTHESIS:

• Transcription Phases
• McGraw-Hill Animation: mRNA Synthesis
• ​HHMI Transcription Advanced Video
• ​​HHMI Transcription Basic Video
• HHMI Translation video
• ****Learn Genetics Animations​

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GENOMICS REVIEW

GENES:

• Genetics Home Reference: Genome Explanation
• 23andMe: Genes

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​GENE EXPRESSION:

• Gene Suppression/Silencing
• Recombinant DNA Explanation
• Learn.Genetics: Measuring Gene Expression
• Alternative Gene Splicing w/Spliceosomes Video